Biggest Challenges

What issues still needs to be overcome for each modality?

What are the biggest challenges you are
facing with the therapeutics you are working on?

There are still a huge number of challenges that need to be overcome within antibody engineering and therapeutics, particularly around novel modalities. New targets/discovery approaches (55%) was the biggest challenge most respondents are facing, closely followed by transitioning from discovery to the clinic (44%).

What are the biggest challenges you are facing with the
therapeutics you are working on? - BY MODALITY

Each different therapeutic modality has a unique set of challenges. New targets/discovery approaches is by far the biggest challenge for those working on immuno-oncology checkpoints (70%), whilst delivery is a challenge for 49% of those working on CAR-T/Cellular therapies, but just 19% of mAbs.