The gut is an important organ system which performs two essential functions: digestion and host defence. Energetic equilibrium of gut environment is very important to stimulate a well-operative and healthy gut. The human body has nearly 100 trillion microorganisms in the intestine, which perform a vital function in maintaining human health and are also responsible for some of the illnesses. The human gut microbiota is a collection of bacteria, bacteriophages, fungi, yeast, protozoa, and viruses. It also performs a key role in the usual gastrointestinal functions of the body, resistance against pathogens, human immunity improvement, and brain development. An imbalanced gut microbiota can lead to several health concerns.
Numerous studies have explored the connection between diet and the gut microbiota. Dietary fibre was employed for its influences on the gastrointestinal physiological functions because of its physiochemical properties and capabilities of fermentation in gut. Bioactive components are suggested to be effective in intestinal and gut-related issues due to their various biological activities, particularly anti-inflammatory, antioxidant, etc.
Turmeric dietary fibre (TDF), curcumin (CUR) and Asafoetida (ASF) have been well-associated with gut health due to their advantageous effects on gastrointestinal inflammatory conditions. Based on their nutritional values, biological and pharmacological significance and safety, an innovative gut health product (ACTBIOME®) was prepared by Aurea Biolabs Private Limited, Cochin, India, using a novel Polar-Nonpolar-Sandwich (PNS®) Technology to improve gastrointestinal and gut health.